Nolan Lab Profiles Small-Molecule Inhibitors Using New Multiplexing Method for DVS Sciences' CyTOF
Stanford University researcher Garry Nolan has developed a cellular barcoding technique for multiplexing mass cytometry experiments on DVS Sciences' CyTOF mass cytometry instrument and has used it to investigate the effects of various small-molecule inhibitors on human peripheral blood mononuclear cells.
Detailed in a paper published in the current edition of Nature Biotechnology, the technique – termed mass-tag cellular barcoding, or MCB – allows for increased throughput and improved reproducibility, Nolan told ProteoMonitor.
Bonislawski, A. "Nolan Lab Profiles Small-Molecule Inhibitors Using New Multiplexing Method for DVS Sciences' CyTOF" Genome Web (2012):