Japan-News

SITC 2018

November 7-11, 2018 | Walter E. Washington Convention Center, Washington, DC

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Your next breakthrough starts here.

Determining the underlying mechanisms of immunotherapeutic response requires a comprehensive approach to understanding the tumor microenvironment (TME).

At Fluidigm, we enable comprehensive cellular and molecular profiling of the immune system and the tumor microenvironment with proven mass cytometry, Imaging Mass Cytometry™ (IMC™) and automated microfluidics solutions.

Whether you seek to target new biomarkers and pathways or to optimize the effectiveness of checkpoint inhibitors, CAR T cells or cancer vaccines, Fluidigm can help you identify new insights to reach your next research breakthrough.

See product presentations
Visit Fluidigm at Booth 213

Exhibit Dates and Hours:
Thursday, November 8: 5:00–6:30 pm
Friday, November 9: 8:00 am–8:00 pm
Saturday, November 10: 8:00 am–8:25 pm


Hyperion Imaging System

Comprehensively interrogate complex cellular phenotypes and their interrelationships in the context of the tumor microenvironment with Imaging Mass Cytometry™.

Hyperion Imaging System


Helios

Deeply profile immune and tumor cell populations for phenotype and function, all in a single tube.

Helios, a CyTOF System


Maxpar® panel kits

Simplify and economize immune profiling with the pre-optimized, 29-marker Maxpar® Human Immune Monitoring Panel Kit and a third-party automated data analysis solution.

Human Immune Monitoring Panel Kit


Advanta assays

Reveal the molecular signatures of tumor immune response using the Advanta™ IO Gene Expression Assay on Biomark™ HD and custom assays.

Advanta IO Gene Expression Assay Kit

Juno™

Achieve significant cost savings and reduced hands-on time with automated NGS library prep.

Juno

Visit posters and presentations featuring Fluidigm technology

Presentations

Thursday, November 8

Time

Title

Presenter, Institution

Session

9:05-9:35 am Harnessing natural killer cells to potentiate antitumor immunity Amir Horowitz, PhD
Icahn School of Medicine at Mount Sinai
Primer on Tumor Immunology/Session I, Generating Anti-Tumor Immunity
2:10-2:40 pm A high-dimensional assay and analysis platform to discover immune correlates of cancer immunotherapy Sacha Gnjatic, PhD
Icahn School of Medicine at Mount Sinai

Primer on Tumor Immunology/Session III, Analysis of Resistance and Response

Friday, November 9

Time

Title

Presenter, Institution

Session

9:50-10:10 am Understanding the tumor immune composition using quantitative and spatially resolved Imaging Mass Cytometry Kurt A. Schalper, MD, PhD
Yale School of Medicine
Session 102
Understanding the Tumor Microenvironment
1:30–1:35 pm Using high dimensional mass cytometry (CyTOF®)
and machine assisted analysis to detect
biomarkers in the immunotherapy of cancer
Katayoun Rezvani, MD, PhD
University of Texas MD
Anderson Cancer Center
Session 211:
Advances in
Immunotherapy of
Hematologic
Malignancies

Saturday, November 10

Time

Title

Presenter, Institution

Session

3:35-4:00 pm Off-the-shelf engineered NK cells for the treatment of cancer Katayoun Rezvani, MD, PhD
University of Texas MD Anderson Cancer Center
Session 211
Advances in Immunotherapy of Hematologic Malignancies
4:30–4:45 pm Identification and profiling of neoantigen-specific
T cells in NSCL cancer patients treated
with atezolizumab
Alessandra Nardin, DVM
immunoSCAPE
Concurrent Session 212:
Advances in
Immunotherapy of Lung,
Head and Neck Cancer

Posters, Hall E*

Poster No.

Title

Authors

P68 Using high dimensional mass cytometry (CyTOF®) and machine assisted analysis to detect biomarkers in the immunotherapy of cancer Carsten Krieg, PhD; Silvia Guglietta; John M. Wrangle, MD; Luis E. Cardenas, BS; Mitchell Levesque; Reinhard Dummer, MD; Burkhard Becher; Mark P. Rubinstein, PhD; Mark Robinson
P111 Streamlined human immune monitoring with mass cytometry: 29 markers in a single tube with automated data analysis Christina Loh, PhD; Thiru Selvanantham, PhD; Leslie Fung; Michelle M. Poulin; C. Bruce Bagwell; Margaret Inokuma; Clare Rogers, MS; Greg Stelzer, PhD; Steven Lott, PhD
P133 Spatially resolved and multiplexed immunoprofiling of NSCLC using imaging mass cytometry reveals distinct functional profile of CD4 and CD8 TILs associated with response to immune checkpoint blockers Franz Villarroel-Espindola, PhD; Miguel F. Sanmamed, MD, PhD; Jonathan Patsenker; Ya-Wei Lin; Brian S. Henick, MD; Jovian Yu; Mark Verburg; Tayf Badri; Jon Zugazagoitia, MD; Daniel E. Carvajal-Hausdorf, MD; Ruth Montgomery, PhD; Roy S. Herbst, MD, PhD; Lieping Chen, MD, PhD; David L. Rimm, MD, PhD; Tal Shnitzer, PhD; Ronen Talmon, PhD; Yuval Kluger, PhD; Kurt A. Schalper, MD, PhD
P140 Deep profiling of Asian NSCLC to identify the tumor antigen-specific T cells and the predictive potential of the patients treated with PD-1/PD-L1 blockade Joe Yeong, Lisda Suteja, Yannick Simoni, Kah Weng Lau, Sherlly Lim, Josh Jie Hua Loh, Angela Takano, Eng Huat Tan, Tony Kiat Hon Lim, S.W. Daniel Tan, Evan W. Newell
P448 Blockade of EphB4-ephrin-B2 interaction remodels the tumor immune microenvironment in head and neck cancers Shilpa Bhatia, Sana Karam
P502 Novel approach of modulating immune cell metabolism in the tumor microenvironment to enhance efficacy of immunotherapy Frank Borriello, Hong Bum Lee, Vincent O’Neill, Ted Kim, James Lederer, Sanghee Yoo
P557 Overcoming genetically-based resistance mechanisms to PD-1 blockade Davis Torrejon, Gabriel Abril-Rodriguez, Jennifer Tsoi, Ameya Champhekar, Giulia Parisi, Gardenia Cheung-Lau, Tom Wohlwender, Mykola Onyshchenko, Beata Berent-Maoz, Catherine Grasso, Begoña Comin-Anduix, Siwen Hu-Lieskovan, Antoni Ribas
P710 Phase 1/2 study of image guided intratumoral CD40 agonistic monoclonal antibody (APX005M) in combination with systemic pembrolizumab for treatment-naïve metastatic melanoma Salah Eddine Bentebibel, Daniel H. Johnson, Srisuda Lecagoonporn, Cara Haymaker, Houssein Safa, Cassian Yee, Rodabe N. Amaria, Sapna Patel, Hussein A. Tawbi, Isabella C. Glitza, Michael Davies, Michael K. Wong, Wen-Jen Hwu, Patrick Hwu, Willem W. Overwijk, Ovid C. Trifan, Chantale Bernatchez, Adi Diab

* Presentation hours:

Odd-numbered: Friday, November 9, 12:45–2:15 pm and 6:30–8:00 pm
Even-numbered: Saturday, November 10, 12:20–1:50 pm and 7:00–8:30 pm

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