Cell-ID Cisplatin contains a mixture of naturally occurring platinum isotopes, and is best detected in the 195 channel. Cisplatin binds covalently to cellular proteins and labels cells with compromised cell membranes to a much greater extent than live cells. Therefore, Cell-ID Cisplatin specifically identifies dead cells when incubated prior to fixation or identifies total cells when incubated following cell fixation and permeabilization. Because cisplatin binds covalently to protein, labeling remains strong through subsequent steps used in downstream mass cytometry staining protocols.
Cell-ID™ Cisplatin—100 µL