CD146, also known as MUC18, S-Endo, MCAM, and Mel-CAM (melanoma cell adhesion molecule), is a 118 kD integral transmembrane glycoprotein in the immunoglobulin superfamily. CD146 is strongly expressed by murine vascular endothelial cells. It is expressed on about 30% of neutrophils and 60% of NK cells. Unlike in humans, CD146 is undetectable on monocytes, dendritic cells, T cells, NKT cells, B cells, or smooth muscle cells in mouse. CD146 has a currently unknown ligand and it has been reported to mediate heterophilic cell adhesion and regulates monocyte transendothelial migration.
Anti-Mouse CD146 (ME-9F1)-141Pr—100 Tests