CD179a, also known as VpreB, is an 18 kDa protein that combines with CD179b (λ5) to form the immunoglobulin surrogate light chain. Through the successful rearrangement of heavy chain genes, pro-B cells undergo differentiation into pre-B cells and start to express a premature antigen receptor, known as the pre-B cell receptor (pre-BCR), consisting of µ, CD179a/b, and the Igα/Igβ heterodimer. Upon further differentiation from pre-B cells to B cells, CD179a/b disappear and are replaced with conventional light chain.
Anti-Human CD179a (HSL96)-149Sm—100 Tests
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Species:Human
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Clone:HSL96
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Target:CD179b
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Tag:149Sm
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Quantity:100 Tests
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