CD107a, also known as lysosome-associated membrane protein 1 (LAMP-1) or LGP-120, is a 110–140 kDa type I membrane glycoprotein. It is expressed by activated platelets and lymphocytes, macrophages, epithelial cells and endothelial cells. It is also expressed by some tumor cells and may play a role in tumor cell metastasis. Upon activation, CD107a is transferred to the cell membrane surface, where it plays a role in cell adhesion and regulation of tumor metastasis and mediates autoimmune disease progression. Antibody clone H4A3 recognizes an epitope of CD107a that can be exposed on the cell surface or intracellularly.
Anti-Human CD107a/LAMP1 (H4A3)-151Eu—25 µg