消耗品

Anti-Human CD268 (11C1)-155Gd—100 Tests

B cell-activating factor receptor (BAFF-R) is a 19 kDa type III membrane protein, also known as CD268. BAFF-R is expressed on mature B cells, B cell lymphoma, and T cell subsets. BAFF-R is one of the receptors for B cell-activating factor (BAFF), a member of the TNF family of proteins. BAFF is a key regulator for B cell differentiation and is critical in the regulation of survival and activation of peripheral B cell populations. Experiments in a mouse model have demonstrated that interaction of BAFF with BAFF-R promotes NF-κB activity. Overexpression of BAFF results in expansion of the B cell compartment and autoimmunity in mice.

  • Species:
    Human
  • Clone:
    11C1
  • Target:
    CD268/BAFF-R
  • Tag:
    155Gd

 

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