GM-CSF, together with G-CSF, M-CSF, IL-3, and IL-5, belongs to the family of hematopoietic cytokines. GM-CSF is secreted by a variety of cell types including monocytes, endothelial cells, activated T and B lymphocytes, fibroblasts, and LPS-stimulated macrophages. GM-CSF function is mediated by binding to a high-affinity receptor composed of the GM-CSF-specific α chain and a β chain that is shared with the IL-3 and IL-5 receptors. In addition to its hematopoietic properties, GM-CSF mediates critical functions in the response to external stimuli, inflammation, and the antitumor response.
Anti-Human GM-CSF (BVD2-21C11)-159Tb—100 Tests
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Species:Human
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Clone:BVD221C11
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Target:GM-CSF
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Tag:159Tb
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Quantity:100 Tests
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