V-Domain Ig Suppressor of T Cell Activation (VISTA), also known as B7-H5, is a 55–65 kDa transmembrane protein belonging to the Ig superfamily, and it has sequence similarity to both the B7 and CD28 family members. VISTA is primarily expressed by myeloid cells. It is also expressed by CD4+, CD8+, and Foxp3+ T cells. It is a negative checkpoint control protein that regulates T cell activation and immune responses. Clone D1L2G™ recognizes endogenous levels of total VISTA protein.
Anti-Human Vista (D1L2G)-160Gd—25 µg