Keratins (cytokeratins) are a group of intermediate filament proteins that are mainly expressed in epithelial cells. Keratin heterodimers composed of an acidic keratin (or type I keratin, keratins 9 to 23) and a basic keratin (or type II keratin, keratins 1 to 8) assemble to form filaments. The composition of pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state. This tissue- and differentiation-specific profiles make them useful as research biomarkers.
Anti-Human Pan-Keratin (C11)-162Dy—50 Tests