CCR6, also known as CD196, is a seven-transmembrane G protein-coupled receptor that belongs to the family of beta chemokine receptors. It is expressed on immature dendritic cells, B lymphocytes, memory T cells, monocytes, macrophages and neutrophils. CCR6 positive cells and its ligand CCL20 have been detected in numerous organs, especially the secondary lymphoid organ. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease.
Anti-Human CD196/CCR6 (Polyclonal)-163Dy—25 µg