CCR7 (CC chemokine receptor type 7), also known as CD197, binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity through their effects on interactions between T cells and dendritic cells. CCR7 is expressed by naive T cells and various cancer cells such as non-small lung cancer, gastric cancer, and esophageal cancer. This expression is linked with metastasis to lymph nodes. Antibody clone G043H7 binds to an epitope of CCR7 when it is expressed on the cell surface.
Anti-Mouse CD197/CCR7 (4B12)-164Dy—50 Tests