Notch3 is a type I membrane protein. The binding of Notch 3 to its ligands results in the proteolysis of Notch and movement of intracellular portions of Notch into the nucleus. This translocation triggers a series of signaling and regulatory processes. Notch 3 is expressed in adult arterial smooth muscle cells.
Anti-Human Notch3 (MHN3-21)-165Ho—100 Tests