B7-H4, also known as VTCN1, is a type I transmembrane protein and member of the B7 family. B7-H4 is a costimulatory protein reported to function as a negative regulator of T cell-mediated immunity. B7-H4 is expressed on activated T cells, B cells, monocytes and dendritic cells. Aberrant expression has been associated with cancers of the lung, breast and ovary in humans. B7-H4 could be a useful prognostic marker in renal cell carcinoma.
Anti-Human B7-H4 (H74)-166Er—25 µg