CLEC10a (C-type lectin domain family 10, member A) is also known as CD301, macrophage galactose/N-acetylgalactosamine (GalNAc) specific lectin (MGL), DCASGPR, and HML. It is a 40 kDa type II transmembrane glycoprotein and is expressed on immature myeloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10a binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.
Anti-Human CD301/CLEC10a (H037G3)-167Er—100 Tests