The monoclonal antibody 58XB4 specifically recognizes human CD104, also known as integrin beta 4 or β4 integrin. CD104 is a 205 kDa type I transmembrane glycoprotein that associates with integrin alpha 6 (CD49f), forming the α6/β4 (CD49f/CD104) heterodimer. CD104 is expressed on epithelial cells and tumor cells and has been shown to mediate cell-cell interactions and interactions between cells and the extracellular matrix. Multiple reports have established a role for CD104 in tumorigenicity.
Anti-Human CD104 (58XB4)-173Yb—100 Tests