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Anti-pS6 [S235/S236] (N7-548)-175Lu—25 µg

Ribosomal protein S6 belongs to the S6E family of ribosomal proteins and is a component of the 40S ribosomal subunit. It plays a role in regulation of translation and thus relates to the growth of cells. Phosphorylation of S6 at multiple C-terminal serine residues, including S235, S236, S240 and S244, activates it. Activated S6 up-regulates ribosomal translation of RNA species. These phosphorylations are mediated by various kinases, including p70S6K and PKCδ, and activated through cellular responses to extrinsic factors. The N7-548 monoclonal antibody specifically detects the S6 ribosomal protein phosphorylated at S235 and S236.

  • Species:
    Cross
  • Clone:
    N7-548
  • Target:
    pS6 [S235/S236]
  • Tag:
    175Lu
  • Sample Type:
    FFPE

 

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