5619 検索結果

• consumable

  Anti-Mouse CD36 (HM36)-147Sm—100 Tests

  CD36, also known as gpIIIb or gpIV, is a member of the class B scavenger receptor family of cell surface proteins that binds to collagens, thrombospondin, oxidized LDL, long-chain fatty acids and apoptotic cells to facilitate their internalization and removal. …

  Product #: 3147018B

• consumable

  Anti-Human/Mouse CD282 (T2.5)-149Sm—100 Tests

  CD282, also known as TLR2, interacts with TLR1 and TLR6 to mediate the innate immune response against pathogens. …

  Product #: 3149022B

• consumable

  Anti-Mouse CX3CR1 (SA011F11)-164Dy—100 Tests

  CX3CR1, also known as GPR13, plays a major role in the survival of monocytes as well as in the adhesion and migration of leukocytes during inflammation. …

  Product #: 3164023B

• consumable

  Anti-Human CD162 (KPL-1)-161Dy—100 Tests

  CD162, also known as SELPLG and PSGL-1, plays an important role in leukocyte adhesion and rolling. …

  Product #: 3161026B

• consumable

  Anti-Mouse CD366/TIM-3 (RMT3-23)-162Dy—100 Tests

  T cell immunoglobulin mucin-3 (TIM-3), also known as CD366, is a type 1 glycoprotein that is expressed on the cells of both innate and adaptive immune system. …

  Product #: 3162029B

• consumable

  Anti-Human/Mouse BCL-6 (K112-91)-163Dy—100 Tests

  BCL-6 is expressed in B and T cells. In B cells, BCL-6 induces proliferation, antibody class switching, and affinity maturation. In T cells, BCL-6 is required for programming of TFH cell generation. …

  Product #: 3163012B

• consumable

  Anti-Human CD257 (T7-241)-163Dy—100 Tests

  CD257, also known as BLyS, a member of the TNF family, is a type II membrane protein that exists in both membrane-bound and soluble forms. It has a molecular weight of approximately 31 kDa. …

  Product #: 3163013B

• consumable

  Anti-Human CD49a/Integrin α1 (TS2/7)-163Dy—100 Tests

  CD49a, also known as α1 integrin or VLA-1 α chain, binds with the integrin β 1 subunit (CD29) to form the α 1/β 1 heterodimer (CD49a/CD29) and serves as receptor for laminin-1 and collagen. …

  Product #: 3163015B

• consumable

  Anti-Human CD301/CLEC10a (H037G3)-167Er—100 Tests

  CD301, also known as CLEC10a (C-type lectin domain family 10, member A), is a transmembrane glycoprotein expressed on immature myeloid dendritic cells and alternatively activated macrophages. …

  Product #: 3167015B

• consumable

  Anti-Human Integrin a9b1 (Y9A2)-168Er—100 Tests

  Integrin α9β1 is expressed on a variety of cell types including airway epithelium cells, different types of muscle cells, hematopoietic stem cells, progenitor cells, and hepatocytes, where it is thought to mediate stem cells adhesion, proliferation, and differentiation. …

  Product #: 3168013B

• consumable

  Anti-Human CD127/IL-7Ra (A019D5)-168Er—100 Tests

  CD127, also known as the IL-7 receptor α chain or IL-7α, is a 60–90 kDa type I transmembrane glycoprotein. …

  Product #: 3168017B

• consumable

  Anti-Mouse CD154/CD40 Ligand (MR1)-170Er—100 Tests

  CD154, also known as CD40 ligand (CD40L), is a 39 kDa type II membrane glycoprotein of the TNF family. …

  Product #: 3170011B

• consumable

  Anti-Human CD54 (HA58)-170Er—100 Tests

  CD54, also known as ICAM-1, is a transmembrane glycoprotein belonging to the immunoglobulin supergene family and is a ligand for Mac-1 (CD11b/CD18) and LFA-1 (CD11a/CD18). …

  Product #: 3170014B

• consumable

  Anti-Human Invariant NKT (6B11)-170Er—100 Tests

  6B11 identifies invariant NKT (iNKT) cells, which are a small subset of T lymphocytes that express other NK cell molecules such as CD161 by binding a unique determinant in the CDR3 region of the invariant (Vα24-JαQ) TCR chain. …

  Product #: 3170015B

• consumable

  Anti-Human B2-microglobulin (2M2)-170Er—100 Tests

  The 2M2 monoclonal antibody binds specifically to β2-microglobulin, a 12 kDa nonpolymorphic Ig-like protein also known as β2M. …

  Product #: 3170016B

• consumable

  Anti-Human CD94 (HP-3D9)-174Yb—100 Tests

  CD94 is expressed on natural killer (NK) cells, NKT cells, and subsets of CD8+ T cells and gamma delta T cells. Up-regulation of CD94 expression appears to correlate with NK cell activation. …

  Product #: 3174015B

• consumable

  Anti-Mouse CD223/LAG3 (C9B7W)-174Yb—100 Tests

  Lymphocyte activation gene-3 (LAG-3), also known as CD223, shares homology with CD4. LAG-3 binding to MHC class II molecules is thought to contribute to the negative regulation of T cell activation. …

  Product #: 3174019B

• consumable

  Anti-Human CD193/CCR3 (5E8)-175Lu—100 Tests

  CD193, also known as CCR3 (CC chemokine receptor type 3), is a high-affinity chemokine receptor for CCL11/eotaxin-1, CCL24/eotaxin-2, and CCL26/eotaxin-3. …

  Product #: 3175025B

• consumable

  Anti-Human CD235ab (HIR2)-175Lu—100 Tests

  CD235a/b, also known as glycophorin isoform A and B, is the major sialoglycoprotein expressed on red blood cell membrane and on erythroid precursors. …

  Product #: 3175027B

• consumable

  Anti-Mouse CD278/ICOS (7E.17G9)-176Yb—100 Tests

  CD278, also known as ICOS, is a member of the CD28 family reacting with inducible co-stimulatory (ICOS) molecule. It is highly expressed on activated T cells. …

  Product #: 3176014B