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User Guide
Access Array for Ion Torrent PGM Sequencing System User Guide
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Quick Reference
Access Array 48.48 IFC 4-Primer Amplicon Tagging Workflow
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User Guide
Access Array for Illumina Sequencing Systems User Guide
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Site Requirements
Juno System Site Requirements
Site Requirements Guide
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User Guide
Juno System User Guide
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technical note
CyTOF 6.7 Data Storage Requirements
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Publications
Impact of recent innovations in the use of mass cytometry in support of drug development
Cytometry by time-of-flight (CyTOF) is a novel technology for the real-time analysis of single cells. …
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Publications
Application of phospho-CyTOF® to characterize immune activation in patients with sickle cell anemia in an ex vivo model of thrombosis
Sickle cell disease (SCD) is a genetic disease caused by mutations in the beta globin gene, and inflammation plays a key role in driving many aspects of disease pathology. …
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Publications
Cytometry: Measure for measure
Cutting-edge tools that can identify the characteristics of cells are helping researchers to develop more-effective vaccines. …
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system
Helios, a CyTOF System
The highest-resolution profiling of cell phenotype and function available …
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Publications
Histone Deacetylase Inhibitors Potentiate Vesicular Stomatitis Virus Oncolysis in Prostate Cancer Cells by Modulating NF-κB-Dependent Autophagy
Vesicular stomatitis virus (VSV) is an oncolytic virus that induces cancer cell death through activation of the apoptotic pathway. …
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faq
Why is the use of CAS and WB Injector only recommended for Helios? Wouldn’t samples run on any mass cytometer benefit from being resuspended in CAS?
Although we have not rigorously tested the use of Cell Acquisition Solution (CAS) with samples run on CyTOF® 2 systems, it is likely that some benefit to cell signal strength and stability would be seen on those systems as well. …
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faq
What are SNP Type Assays?
SNP Type Assays are allele-specific PCR assays made by Fluidigm that use three primers and two universal probes to distinguish between two alleles. …
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User Guide
D3 Assay Design User Guide
D3 Assay Design User Guide 100-6812
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Publications
Role of immune aging in susceptibility to West Nile virus
West Nile virus (WNV) is a mosquito-borne enveloped positive-strand RNA virus belonging to the family Flaviviridae, which includes Yellow fever, hepatitis C, and Dengue viruses. …
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Publications
The natural killer cell response to West Nile virus in young and old individuals with or without a prior history of infection
West Nile virus (WNV) typically leads to asymptomatic infection but can cause severe neuroinvasive disease or death, particularly in the elderly. …
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Publications
Activation of Salmonella Typhi-Specific Regulatory T Cells in Typhoid Disease in a Wild-Type S. Typhi Challenge Model
Salmonella Typhi (S. Typhi), the causative agent of typhoid fever, causes significant morbidity and mortality worldwide. …
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Publications
The Split Virus Influenza Vaccine rapidly activates immune cells through Fcγ receptors
Seasonal influenza vaccination is one of the most common medical procedures and yet the extent to which it activates the immune system beyond inducing antibody production is not well understood. …
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Publications
Brief Report: Chikungunya viral arthritis in the United States: A mimic of seronegative rheumatoid arthritis
Chikungunya virus (CHIKV) is an arthritogenic mosquito-transmitted alphavirus that spread to the Caribbean in 2013 and to the US in 2014. …
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Publications
High-dimensional immune profiling of total and rotavirus VP6-specific intestinal and circulating B cells by mass cytometry
In-depth phenotyping of human intestinal antibody secreting cells (ASCs) and their precursors is important for developing improved mucosal vaccines. …